OneVit Vitamin B12

OneVit Vitamin B12 contains methylcobalamin, which is a naturally occurring, active form of vitamin B12.

The unique molecular structure of methylcobalamin allows for immediate absorption without the need for conversion into another compound.

This enables methylcobalamin to directly influence metabolic processes, facilitating faster utilisation by the body.

In contrast, cyanocobalamin is a synthetic form of vitamin B12 that requires conversion into methylcobalamin by the liver before it can take effect in the body.

This additional step can take several hours, depending on individual metabolic factors, which can delay the onset of its benefits.

Some of the most common symptoms of vitamin B12 deficiency include:

• Fatigue and weakness - Low levels of vitamin B12 disrupt energy metabolism because it is essential for red blood cell production. Without enough red blood cells, oxygen transport is reduced, limiting the oxygen available for cellular respiration, which impairs energy production.
• Pale skin - Vitamin B12 deficiency can lead to a decrease in the production of healthy red blood cells, a condition known as anaemia. Without sufficient B12, the body produces larger-than-normal red blood cells that are inefficient at delivering oxygen to tissues and organs, making the skin appear pale.
• Shortness of breath and dizziness - A deficiency in Vitamin B12 reduces the number of healthy red blood cells that transport oxygen to tissues and organs, leading to hypoxia. Consequently, the body increases the breathing rate to compensate, resulting in shortness of breath. The diminished oxygen supply to the brain can cause dizziness or lightheadedness, especially during physical exercise.
• Numbness or tingling in the hands and feet - Vitamin B12 is essential for maintaining the myelin sheath, a protective layer that surrounds and insulates nerve fibres. When vitamin B12 levels are low, the myelin sheath deteriorates, leading to nerve damage and disrupting the transmission of nerve signals. This can result in numbness and tingling sensations in the hands and feet.
• Cognitive difficulties - Vitamin B12 supports the synthesis of serotonin and dopamine, neurotransmitters that regulate mood and cognition. Vitamin B12 deficiency disrupts the process of neurotransmitter formation (methylation) which can result in memory loss, confusion and difficulty concentrating.
• Muscle weakness - Vitamin B12 deficiency can lead to insufficient oxygen reaching muscles due to low red blood cell counts, impairing cellular respiration and reducing the energy available for muscle contraction. Additionally, nerve damage from the breakdown of the myelin sheath can affect neuronal signals necessary for efficient motor function, further contributing to muscle fatigue.

• Energy levels - Vitamin B12 supports metabolic processes involved in converting proteins, carbohydrates and fats into adenosine triphosphate, the primary energy source for cells. This mechanism subsequently helps improve energy levels, reducing tiredness and fatigue.
• Nerve function - Vitamin B12 is crucial for the synthesis of myelin, a protective sheath that surrounds and insulates nerve fibres. Myelin allows for the rapid transmission of electrical signals between nerve cells, ensuring effective communication within the nervous system.
• Red blood cell formation - Vitamin B12 supports DNA synthesis, which is essential for the rapid production of healthy red blood cells. Red blood cells contain haemoglobin, the protein responsible for transporting oxygen throughout the body, improving cellular respiration and energy production.

Take one tablet of OneVit Vitamin B12 per day, ensuring consistent use to maximise the positive effects of this supplement.

It is not necessary to take more than this amount per day, as each OneVit Vitamin B12 tablet contains 40,000% of the Nutrient Reference Value for vitamin B12, which is more than sufficient to prevent a deficiency.

The time it takes to notice the desired effects of OneVit Vitamin B12 can vary from person to person and depends on several factors, including:

• Metabolism - OneVit B12 contains vitamin B12 in the biologically active form of methylcobalamin, meaning it does not require conversion in the body such as other forms such as cyanocobalamin. This ensures more efficient absorption and utilisation of vitamin B12 in the body, which is particularly beneficial for individuals who may have difficulty converting other vitamin forms due to genetic factors, age or certain health conditions.
• Diet - Vitamin B12 must pass through the stomach undigested to be optimally absorbed in the small intestine. Protein facilitates this process by causing the body to produce ‘intrinsic factor’, a molecule that binds to vitamin B12 in the stomach, protecting it from being broken down. This implies that individuals who consume a high amount of protein as part of their diet are more likely to notice the benefits of OneVit Vitamin B12 faster.
• Existing health conditions - Certain conditions, such as Pernicious Anaemia, can affect the body's utilisation of vitamin B12, due to their effects on the production of proteins that are necessary for the absorption of the methylcobalamin in OneVit Vitamin B12. In such cases, the body may struggle to absorb adequate amounts of B12 from food or supplements, delaying the onset of its benefits.
• Medication usage - Certain medications can interfere with vitamin B12 absorption or metabolism. For example, long-term use of proton pump inhibitors (PPIs), used to treat acid reflux, or metformin, used for diabetes, can reduce stomach acid levels, impairing B12 absorption. Vitamin B12 requires sufficient stomach acid for effective absorption, therefore, individuals taking these medications may need more time or higher doses to experience the benefits.

OneVit Vitamin B12 is suitable for use by all individuals, including vegetarians and vegans. Individuals who are pregnant, breastfeeding, or taking medication should consult a doctor before taking OneVit Vitamin B12.

The following supplements can complement and amplify the benefits of OneVit Vitamin B12:

• OneVit Iron - Iron can complement OneVit Vitamin B12 by aiding red blood cell formation and haemoglobin production. Together, these nutrients optimise oxygen transportation throughout the body, which supports energy levels and reduces fatigue.
• OneVit Magnesium - Magnesium aids nerve relaxation and can calm nervous system activity, complementing the potential for OneVit Vitamin B12 to enhance mental clarity and aid cognitive functioning.