Differin (Adapalene) 0.1%

Differin (Adapalene) Is A Powerful, Highly Effective Acne Treatment

Differin (Adapalene) 0.1%
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Differin (Adapalene) gel and cream are effective acne treatments, clinically proven to clear and prevent mild to moderate acne.
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What is Differin and how does it help to clear my acne?

Differin contains the active ingredient Retinoid Adapalene, which is clinically proven to clear and prevent mild to moderate acne. Adapalene is an anti-inflammatory medicine, highly effective at reducing the formation of whiteheads and blackheads on the outer layer of skin. Differin is non-comedogenic and fragrance-free; it actively helps to prevent breakouts, whiteheads, blackheads, clogged pores and blemishes. Differin is ideal for daily use in either a gel or cream to remove acne and return skin back to its healthy tone and texture.

What are the benefits of Differin (Adapalene) gel and cream?

  • Contains Retinoid Adapalene to actively clear acne.
  • Prevents breakouts, whiteheads, blackheads, clogged pores and blemishes.
  • Restores skin tone and texture.
  • Non-comedogenic.
  • Fragrance-free.

How long does it take to start seeing results while using Differin?

As with all acne medication, results may not be seen before 12 weeks. However, in many cases, results can be observed following continued use during a 12 week period. It is important to use Differin consistently and continually to ensure you get the best results.

How do I use Differin (Adapalene) gel and cream?

Apply a thin layer of Differin cream or gel once a day, all over your face. For practicality, application before bedtime is recommended.

Be careful not to apply Differin to sensitive areas such as the mouth, nostrils or eyes. Take care to wash your hands before and after use. Do not apply Differin to broken skin. Temporary skin irritation (retinization) can occur while adjusting to the active ingredient, this should subside by week 4. Always read the patient information leaflet before use and seek further professional advice if necessary.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Written and reviewed by our qualified team

GPhC Number: 2088658

Ana Carolina Goncalves
Authored by: Ana Carolina Goncalves Superintendent
Pharmacist

GPhC Number: 2225869

Rehma Gill
Reviewed by: Rehma Gill Pharmacy
Manager

Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 11 Apr 2025

Differin Reviews

Overall Rating
9.6 / 10
Ratings Distribution
5 stars
157
4 stars
22
3 stars
3
2 stars
0
1 star
0

Based on 182 independent customer reviews taken by Feefo, Google and Trustpilot.

Truspilot logo
Google logo
Feefo logo
"Excellent quality"

Product Review:

Effective.

Service Review:

Excellent quality

Review from: Trustpilot

TickVerified Buyer

"Excellent speedy delivery"

Product Review:

Great quick delivery!

Service Review:

Prompt in every way

Review from: Feefo

TickVerified Buyer

"Asked the rite questions and speedy…"

Product Review:

Effective after few months off using

Service Review:

Asked the rite questions and speedy delivery

Review from: Trustpilot

TickVerified Buyer

Product Review:

Filled in the online form and placed my order, it was quick and easy to do. Fair pricing and quick delivery. Have used this cream before but first time ordering from Pharmacia. Will use again.

Review from: Feefo

TickVerified Buyer

Product Review:

Excellent service. Fast and reliable at a reasonable price.

Review from: Feefo

TickVerified Buyer

"Differin gel"

Product Review:

The gel is excellent for acne. Delivery was quick too. Thank you!

Service Review:

Very quick and smooth purchase process.

Review from: Feefo

TickVerified Buyer

"Very fast efficient service"

Product Review:

Very good product and gentle on very sensitive skin

Service Review:

Very fast efficient service

Review from: Trustpilot

TickVerified Buyer

Product Review:

Love this product

Review from: Trustpilot

TickVerified Buyer

"Fantastic service"

Product Review:

Absolutely brilliant - very fast delivery.

Service Review:

Fantastic service - clear and fast.

Review from: Feefo

TickVerified Buyer

"Product was excellent as described…"

Product Review:

This product is excellent. Have suffered from milia spots for years and have seen a huge improvement in as little as 2 weeks and improving all the time. Highly recommend.

Service Review:

Great product description excellent service

Review from: Trustpilot

TickVerified Buyer

Discreet service

Discreet Packaging

Your privacy is important to us. That’s why we’ve taken every step to ensure your order arrives in the most discreet way possible.

From start to finish, your purchase is handled with complete confidentiality. You’ll never see our brand name on your bank statement, bills or delivery papers.

All our parcels are sent in plain, unmarked packaging with no logos, no product descriptions and no indication of what’s inside.

Estimated delivery

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£2.90 - Friday 25 April

Collect from your Post Office

£3.95 - Friday 25 April

Special Delivery 1pm Guaranteed

£5.95 - Friday 25 April by 1pm

Special Delivery 9am Guaranteed

£13.95 - Friday 25 April by 9am

Same Day Delivery

from £4.95 - Thursday 24 April

How does it work?

How it works - Consultation

Online consultation

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How it works - Delivery

Express delivery

Medication is dispensed and delivered to your home or work

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